| Factor VIII Inhibitor, EIA Screen and Factor VIII Actvity, Clotting |
| If Factor VIII Inhibitor, EIA Screen is positive, Factor VIII Human Inhibitor will be performed at an additional charge (CPT code(s): 85335). If Factor VIII Human Inhibitor is <2.1 or > 0.4, Nijmejan Assay will be performed at an additional charge (CPT code(s): 85335). |
CPT Code(s):
85335; 85240
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Specimen Container:
3.2% Sodium Citrate (light blue-top)
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Preferred Specimen:
2 mL plasma in 3 separate tubes
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Transport Temperature:
Frozen
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Clinical Use:
The presence of alloantibodies against factor VIII activity is a complication of treatment in hemophilia A, while the presence of autoantibodies may develop spontaneously in patients with acquired Factor VIII-C deficiency. The detection of Factor VIII inhibitor is of importance in these patients. Factor VIII inhibitor EIA assay is a quick method for the detection of Factor VIII inhibitor. |
